The following solvent accessibility information was derived from the information in Table 2 of reference . The data for this table was calculated from data taken from 55 proteins in the Brookhaven data base, coming from 9 molecular families: globi ns, immunoglobins, cytochromes c, serine proteases, subtilisins, calcium binding proteins, acid proteases, toxins and virus capsid proteins. Red entries are found on the surface of a proteins on > 70% of occurrences and blue entries are found inside of a protein of < 20% of occurrences.
NOTE: These two conditions ARE NOT equivalent!
The only clear trend in this table is that some residues, such as R and K, locate themselves so that they have access to the solvent. The so-called hydrophobic residues, such as L and F, show no clear trend: they are found near the solvent as
often as they are found buried.
|Amino acid||SEA > 30 Ň2||SEA < 10 Ň2||30 > SEA > 10 Ň2|